Smith’s final appearance as Dr. Callie Torres’ flame comes in this Thursday’s episode of ABC’s medical drama, the network said Monday.
Smith’s departure from Grey’s Anatomy was first reported by Entertainment Weekly.
The actress, who first appeared on the show in 2006, told the magazine she’d had high hopes for the fictional lesbian pair.
“I was very excited when they told me that Erica and Callie were going to have this relationship. And I really hoped we were going to show what happens when two women fall in love and that they were going to treat it like any heterosexual couple on TV,” she said.
“And so I was surprised and disappointed when they just suddenly told me that they couldn’t write for my character any more,” she said.